BDBM245543 US9428503, 63

SMILES CO[C@H]1CC[C@@H](C1)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN(C)C)nc2)n(C)c1=O

InChI Key InChIKey=UAWYNAAMALKRLO-OALUTQOASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 245543   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM245543(US9428503, 63)
Affinity DataIC50:  1.08E+4nMT: 2°CAssay Description:Assay d) MDA-MB-468 cells (human breast adenocarcinoma ##ATCC HTB 132) were seeded at 1500 cells/well in 40 μl of DMEM containing 10% FBS and 1% g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent